Substance	Endpoint of concern	In vivo	Other
1,2-Benzenedicarboxylic acid, benzyl isononyl alkyl esters	CMR	OECD TG 422
2,2′,6,6′-Tetra-tert-butyl-4,4′- methylenedipheno	CMR; ED; PBT/vPvB/sensitiser	OECD TG 443	OECD TG 307
2,5-di-tert-pentylhydroquinone (DAHQ)	PBT/vPvB Skin sensitisation	Round 1: (OECD TG 210); (OECD TG 305); OECD TG 429	Round 1: OECD TG 105; OECD TG 123; OECD TG 201; OECD TG 211; OECD TG 309; OECD TG 106 Round 2: OECD TG 104; OECD TG 105; OECD TG 123; Calculation of HLC
2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-propanediyl diacrylate	Sensitiser Became mutagenicity and PBT	OECD TG 489; (OECD TG 203); (OECD TG 305)
4,4'-sulfonyldiphenol	CMR; ED	OECD TG 443; OECD TG 417; OECD TG 489
4-tert-butylphenol	ED	OECD TG 408
Benzene, mono-C10-13-alkyl derivs., distn. residues	PBT/vPvB	(OECD TG 222); OECD TG 208	OECD TG 307; OECD TG 316
C16-(branched), C20-(branched) and C24-(branched)-alkanes	PBT/vPvB		1st round: OECD TG 310 2nd round: OECD TG 309; OECD TG 308
Climbazole	CMR	1st round: OCED TG 443 2nd round: (OECD TG 234)	1st round: OECD TG 303A or B; OECD TG 456; Stably Transfected Human Androgen Receptor Transcriptional Activation Assay for Detection of Androgenic Agonist and Antagonist Activity of Chemicals (Draft OECD Test Guideline due for finalisation in 2016), if adopted by time of testing Or US EPA OPPTS 890.1150
Di-tert-butyl 3,3,5-trimethylcyclohexylidene diperoxide	PBT/vPvB		1st round: OECD TG 105; OECD TG 309 or OECD TG 308 2nd round: OECD307
Dimethyl disulphide	Exposure of environment
Ditolyl ether	PBT/vPvB	(OECD TG 210)	OECD TG 104; OECD TG 309; OECD TG 305; OECD TG 201
Diuron	ED	1st round: (OECD TG 234) 2nd round: (OECD TG 241)
Ethyl methacrylate	CMR; sensitisation		OECD TG 471; OECD TG 487; OECD TG 476 or OECD TG 490
Imidazolium compounds, 2-C17-unsatd.-alkyl-1-(2-C18-unsatd. amidoethyl)-4,5-dihydro-N-methyl, Me sulfates	PBT/vPvB	(OECD TG 225)	1st round: OECD TG 106; OECD TG 301; OECD TG 211; OECD TG 111 2nd round: ISO 22030; OECD TG 220 or OECD TG 222
Methyl 4-hydroxybenzoate	CMR; ED	(OECD TG 234)
N,N'-dithiodi-o-phenylenedibenzamide	PBT/vPvB		OECD TG 309; OECD TG 307
p-(1,1-dimethylpropyl)phenol	ED	OECD TG 408
Phenol, 4-nonyl-, branched	PBT/vPvB	(OECD mollusc reproduction test); (ICES TIMES 54 or US EPA OPTTS850.1055) (EPS 1/RM/27)	OECD TG 115
phenol, styrenated,reaction mass of 2,4,6-tris(1-phenyl-ethyl)phenol and Bis(1-phenylethyl) phenol	ED; PBT/vPvB	(OECD TG 210); (OECD TG 234)	OECD TG 123; OECD TG 115; OECD TG 309 or OECD TG 308
S-(tricyclo[5.2.1.0 2,6]deca-3-en-8(or 9)-yl) O-(isopropyl or isobutyl or 2-ethylhexyl) O-(isopropyl or isobutyl or 2-ethylhexyl)phosphorodithioate	PBT/vPvB		OECD TG 105; OECD TG 309; OECD TG 307
Shale Oil Bitumen	CMR; PBT/vPvB
Silver	Other	(OECD TG 211)	OECD TG 201; OECD TG 216; OECD GD 29; OECD TG 109; Fate in soil pore water and solid soil
Tert-butyl methyl ether	ED	OECD TG 488; (OECD TG 234)
Tris(methylphenyl) phosphate	1st round: PBT 2nd round skin absorption and neurotoxicity	2nd round: OECD TG 428; OECD TG 424
Trixylyl phosphate	PBT/vPvB	(OECD TG 305)	OECD TG 301; OECD TG 309; OECD TG 307; OECD TG 222 or 220 or 232; OECD TG 216
1,2,4-triazole	CMR; other		OECD TG 456
1-[4-(1,1-dimethylethyl)phenyl]-3-(4-methoxyphenyl)propane-1,3-dione	PBT/vPvB	1st round: (OECD TG 210) 2nd round: (OECD TG 231)	1st round: OECD TG 309; OECD TG 308; OECD TG 211
2,2'-[(1-methylethylidene)bis(4,1-phenyleneoxymethylene)]bisoxirane	CMR; ED	OECD TG 488; OECD TG 489
2,2,6,6-tetrabromo-4,4-isopropylidenediphenol	Reprotoxic; ED, PBT/vPvB	2nd round: (OECD TG 305)	1st round: OECD TG 112; OECD TG 105; OECD TG 123; OECD TG 309 or OECD TG 308; OECD TG 307
2,3-epoxypropyl neodecanoate	CMR; sensitiser	OECD TG 488
3-trimethoxysilylpropyl methacrylate	Sensitiser	OECD TG 429; OECD TG 489
6,6'-di-tert-butyl-4,4'-thiodi-m-cresol	CMR; ED; PBT/vPvB	OECD TG 443; (OECD TG 234)	OECD TG 309
[1,3(or 1,4)-phenylenebis(1-methylethylidene)]bis[tert-butyl] peroxide	PBT/vPvB	(OECD TG 210)	OECD TG 309; OECD TG 305; OECD TG 211
Aluminium chloride	CMR	OECD TG 413; OECD TG 474; OECD TG 489
Aluminium chloride basic	CMR	OECD TG 474; OECD TG 489
Aluminium sulphate	CMR; sensitiser	OECD TG 474; OECD TG 489
bis(2-ethylhexyl) 4,4’-{6-[4-tert-butylcarbamoyl)anilino]-1,3,5-triazine-2,4-diyldiimino}dibenzoate	PBT/vPvB		OECD TG 308
bis(α,α-dimethylbenzyl) peroxide	PBT/vPvB	(OECD TG 305)	OECD TG 309
decamethyltetrasiloxane	PBT/vPvB	(OECD TG 218); (OECD TG 225)	OECD TG 308
di-tert-pentyl peroxide	Carcinogen, mutagen		OECD TG 487
dodecamethylpenta-siloxane	PBT/vPvB	(OECD TG 218)	OECD TG 308; ASTME1706-95b
Hexafluoropropene	CMR		OECD TG 487
m-xylene	CMR; sensitiser
Methyl salicylate	CMR; Became eye irritation		OECD TG 491
o-xylene	CMR; sensitiser
Octamethyltrisiloxane	PBT/vPvB		OECD TG 308
p-xylene	CMR; sensitiser
propyl 4-hydroxybenzoate	Reprotoxicity; ED	OECD TG 443; (OECD TG 234)	OECD TG 211
Quaternary ammonium compounds, di-C16-18-alkyldimethyl, chlorides	other
Reaction mass of 4,4'-methylenediphenyl diisocyanate and o-(p-isocyanatobenzyl)phenyl isocyanate / methylene diphenyl diisocyanate	CMR; PBT/vPvB; sensitiser	OECD TG 489
Resin acids and Rosin acids, hydrogenated, esters with glycerol	PBT/vPvB	(OECD TG 305)	OECD TG 310; OECD TG 309; OECD TG 211
Resin acids and Rosin acids, hydrogenated, esters with pentaerythritol	PBT/vPvB	(OECD TG 305)	OECD TG 310; OECD TG 309; OECD TG 211
1,3-dioxolane	Mutagen; reprotoxic; Became skin and eye irritation		OECD TG 439; OECD TG 437
2,2',6,6'-Tetrabromo-4,4'-isopropylidenediphenol, oligomeric reaction products with Propylene oxide and n-butyl glycidyl ether	ED; PBT/vPvB	(OECD TG 305)
2,3-epoxypropyl o-tolyl ether	Mutagen; added skin sensitisation	OECD TG 429; OECD TG 488
2-Ethylhexyl trans-4-methoxycinnamate	ED; PBT/vPvB	(OECD TG 231 or 241); (OECD TG 234)	OECD TG 211
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl acrylate	ED; PBT/vPvB	(OECD TG 234); (OECD TG 231)
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl methacrylate	ED; PBT/vPvB	(OECD TG 234); (OECD TG 231)
a mixture of: 4-(2,2,3-trimethylcyclopent-3-en-1-yl)-1-methyl-2-oxabicyclo[2.2.2]octane; 1-(2,2,3-trimethylcyclopent-3-en-1-yl)-5-methyl-6-oxabicyclo[3.2.1]octane; spiro[cyclohex-3-en-1-yl-[(4,5,6,6a-tetrahydro-3,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]furan]; spiro[cyclohex-3-en-1-yl-[4,5,6,6a-tetrahydro-4,6',6',6'a-tetramethyl)-1,3'(3'aH)-[2H]cyclopenta[b]]furan]	PBT/vPvB	(OECD TG 305); (OECD TG 210)	OECD TG 309; OECD TG 211
Benzenamine, N-phenyl-, reaction products with 2,4,4-trimethylpentene	PBT/vPvB	(OECD TG 305); (OECD TG 210)	OECD TG 105; OECD TG 123; OECD TG 309; OECD TG 211; OECD TG 201
Benzotriazole	ED	(OECD TG 234)
benzyl alcohol	sensitiser
Ethyl 3,5-dichloro-4-hexadecyloxycarbonyloxybenzoate	PBT/vPvB		OECD TG 301; OECD TG 105; OECD TG 309; OECD TG 307
Ethylene dinitrate	Reprotoxic; ED; PBT/vPvB; sensitiser
Isopentyl p-methoxycinnamate	ED	(OECD TG 231 or 241); (OECD TG 234)
methacrylamide	other	OECD TG 426
O,O,O-triphenyl phosphorothioate	PBT/vPvB	(OECD TG 210); (OECD TG 305)	OECD TG 309; OECD TG 211
Phenol, 4-methyl-, reaction products with dicyclopentadiene and isobutylene	PBT/vPvB	(OECD TG 305); (OECD TG 210)	OECD TG 105; OECD TG 309; OECD TG 307; OECD TG 211
reaction mass of 2,2,3,3,5,5,6,6-octafluoro-4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)morpholine and 2,2,3,3,5,5,6,6-octafluoro-4-(heptafluoropropyl)morpholine	PBT/vPvB	(OECD TG 305)
Tin sulphate	CMR; sensitiser	OECD TG 408; OECD TG 475
2,4-di-tert-butylphenol	CMR; ED	OECD TG 489; (OECD TG 234)
ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate	Became carcinogenicity	OECD TG 451
Dicyclohexyl phthalate	ED	(OECD TG 234)
Potassium titanium oxide (K2Ti6O13)	carcinogenicity	OECD TG 413
quaternary ammonium compounds, tri-C8-10-alkylmethyl, chlorides	PBT/vPvB	(OECD TG 305)	MT 181; OECD TG 309
reaction mass of 1-(1,2,3,4,5,6,7,8-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one and 1-(1,2,3,4,6,7,8,8a-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one and 1-(1,2,3,5,6,7,8,8a-octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one	Reprotoxic; ED; PBT/vPvB	OECD TG 489	OECD TG 309
Sepisol Fast Blue 85219	PBT/vPvB		OECD TG 105
Triphenyl phosphate	ED	(OECD TG 234)
Zinc oxide	Other, became mut	OECD TG 413 OECD TG 489	OECD GD; OECD TG 318; OECD TG 201; OECD TG 211
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione	ED	(OECD 231)
1,3-dihydro-4(or 5)-methyl-2H-benzimidazole-2-thione, zinc salt	ED	(OECD 231)
2,5,7,10,11,14-hexaoxa-1,6-distibabicyclo[4.4.4]tetradecane	Carcinogen; reprotoxic	OECD TG 408; OECD TG 417
3-ethoxy-1,1,1,2,3,4,4,5,5,6,6,6-dodecafluoro-2-(trifluoromethyl)-hexane	PBT/vPvB		OECD TG 308
3-methylpyrazole	Reprotoxic; ED		Alcohol dehydrogenase inhibition in vitro assay
Antimony	Carcinogen	OECD TG 413; OECD TG 417
Antimony sulphide	Carcinogen	OECD TG 413; OECD TG 417
Butanone	Reprotoxic; ED	OECD TG 426
Diantimony trioxide	Carcinogenic	OECD TG 489; OECD TG 474
Titanium dioxide	Carcinogenic, mutagen	Intratracheal instillation study combined with comet assay
1-phenylethanol	Carcinogenic; mutagenic	OECD TG 474	OECD TG 487
6,6'-di-tert-butyl-4,4'-butylidenedi-m-cresol	Reprotoxic; ED; PBT/vPvB	OECD TG 408
A mixture of: propan-2-one-O,O'(methoxyvinylsilandiyl)dioxime; propan-2-one-O-(dimethoxyvinylsilyl)oxime; propan-2-one-O,O',O''-(vinylsilantriyl)trioxime	PBT/vPvB	(OECD TG 305)	OECD TG 307
Bis(2-ethylhexyl)amine	PBT/vPvB		OECD TG 301
methylethylketone peroxide trimer	PBT/vPvB	(OECD TG 305)	OECD TG 309
N,N-diethylhydroxylamine	Carcinogen; mutagen	OECD TG 489
N-[4-[(9,10-dihydro-4-hydroxy-9,10-dioxo-1-anthryl)amino]phenyl]acetamide	PBT/vPvB		OECD TG 309; OECD TG 308
Resorcinol	ED	(OECD TG 241)
1-(5,6,7,8-tetrahydro-3,5,5,6,8,8-hexamethyl-2-naphthyl)ethan-1-one	ED	(OECD TG 234)
3-aminophenol	Mutagen; sensitiser	OECD TG 489
5-amino-o-cresol	Mutagen; sensitiser	OECD TG 489
Bis(2-propylheptyl) phthalate	ED	(OECD TG 231)
Perfluamine	PBT/vPvB	(OECD TG 305)
Phenol, isopropylated, phosphate (3:1)	ED; PBT/vPvB		OECD TG 301
1,2,3,4-Tetrahydro-6-(1-phenylethyl)naphthalene	PBT/vPvB		OECD TG 123
1,2,3,4-Tetrahydro-6-(1-phenylethyl)naphthalene	Reprotoxic; ED	(OECD TG 229); (OECD TG 234)
Reaction products of diphenylamine with nonene, branched	Mutagen; PBT/vPvB		OECD TG 211
1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylindeno[5,6-c]pyran	ED; PBT/vPvB	(OECD TG 241)
2-furaldehyde	Carcinogen; mutagen	OECD TG 488